ImmuCheck Troponin I New Cardiac Marker of Choice

  • Myocardial infarction (MI) is defined as myocardial cell death (necrosis) due to prolonged ischemia. It is recognized by the presence of different proteins (cardiac biomarkers) in the blood that are released from the damaged myocytes. The best available biomarkers are cardiac Troponin I, cardiac Troponin T, CK-MB and Myoglobin.
  • Troponins are structural proteins that act to regulate cardiac muscle contraction. There are three isoforms: Troponin C, Troponin I and Troponin T. They are released into the bloodstream from injured muscle cells during cardiac ischemia. In contrast to Troponin C, the isoforms cTnI and cTnT are specific to cardiac muscles and do not overlap with skeletal muscles.
WHO criteria for the diagnosis of Acute Myocardial Infarction (AMI) is based on the detection of at least 2 out of 3 infarction specific findings:
  • Chest pain> 20 mins
  • Development of Q waves in ECG
  • Elevation of cardiac enzymes (cardiac biomarkers) as recognition of acute MI is important for prognosis & therapy selection, measurement of cardiac necrosis markers is indicated in all patients with acute coronary syndrome wherein:
    • Cardiac Troponin is preferred cardiac necrosis marker
    • CK-MB is acceptable alternative when cTn is not available.

Available in 5 and 20 Tests pack size