Chikungunya: Clinical Aspects!!



ImmuCheck Chikungunya IgM ELISA helps in early diagnosis of infection in acute phase
    IgM antibody detection helps in early diagnosis of infection and helps in stopping further transmission of virus thus containing the infection. A positive IgM result is indicative of a current infection since IgM antibodies are detectable after a mean period of 2 days and persist for a period ranging from several weeks to 3 months.
Laboratory criteria for the diagnosis of Chikungunya (WHO Recommendations) At least one of the following tests in the acute phase should be positive:
  • Virus isolation
  • Presence of viral RNA by RT-PCR
  • Presence of virus specific IgM antibodies in single serum sample collected in acute or convalescent stage.
  • Four-fold rising of IgG titers in samples collected at least three weeks apart.
Key facts!!
  • Chikungunya is a viral disease transmitted to humans by infected mosquitoes.
  • It causes fever and severe joint pain. Other symptoms include muscle pain, headache, nausea, fatigue and rash.
  • Joint pain is often debilitating and can vary in duration.
  • The disease shares some clinical signs with dengue, and can be misdiagnosed in areas where dengue is common.
  • There is no cure for the disease. Treatment is focused on relieving the symptoms.
  • The proximity of mosquito breeding sites to human habitation is a significant risk factor for chikungunya.